Genomic instability is the main risk factor for tumor development in humans. Therefore understanding its origin and and exploring therapeutic targets is paramount. Histone 1 silences a region of the genome that causes irreparable DNA damage when translated and is lethal for the organism.
By combining an FDA-approved cancer immunotherapy with an emerging tumor-roasting nanotechnology, researchers improved the efficacy of both therapies in a proof-of-concept study using mice. The potent combination also attacked satellite tumors and distant cancerous cells, completely curing two mice and effectively vaccinating one against the disease.
Researchers have developed a new terahertz imaging approach that, for the first time, can acquire micron-scale resolution images while retaining computational approaches designed to speed up image acquisition.
A new Pathology Atlas is launched today with an analysis of all human genes in all major cancers showing the consequence of their corresponding protein levels for overall patient survival. The difference in expression patterns of individual cancers observed in the study strongly reinforces the need for personalized cancer treatment based on precision medicin […]