According to a new study, extra DNA scooped up and copied alongside cancer-causing genes helps keep tumors going -- elements that could represent new drug targets for brain tumors and other cancers notoriously difficult to treat.
Researchers have devised a new, promising plan of attack against deadly childhood brain cancers called diffuse midline gliomas (DMG). Scientists have shown that combining two drugs killed DMG patient cells grown in the laboratory and in animal models. The drugs countered the effects of a genetic mutation that causes the diseases. Their studies also uncovered […]
Killer cells of the immune system detect and kill infected cells or cancer cells. Researchers have now discovered that the mechanism by which certain immune cells kill their target cells can also be used to control the killer cells themselves. This finding may be relevant to cancer immunotherapy.
A new screening system developed by scientists leverages redundancy in an important component of a cell - nucleotide metabolism - to help identify new drugs that specifically and potently block processes that are essential for cancer cell growth.
Researchers have demonstrated that an imbalance in the gut microbiota, also known as 'dysbiosis', promotes the onset of colorectal cancer. The teams demonstrated that transplanting fecal flora from patients with colon cancer into mice caused lesions and epigenetic changes characteristic of the development of a malignant tumor. The pilot study led t […]