A study detected in tumoral tissue hundreds of RNAs that do not encode proteins but appear to regulate effects of androgens and androgen receptors on gene expression in tumors. By investigating the connection between the presence of these molecules and tumor aggressiveness, the research paves the way for new scientific approaches focusing on the transcriptio […]
New fundamental complex in cells drives 'messy' form of DNA repair. In immune cells, this is crucial to make antibodies. In cancer, mutations in complex could lead to resistance to BRCA-targeting PARP inhibitor drugs or platinum chemotherapies.
A deadly feature of acute lymphoblastic leukemia (ALL) is its invasion of the central nervous system. ALL in the central nervous system is very difficult to treat, because most drugs are blocked from the organ system due to a "blood-brain barrier" designed to protect the brain. How cancer cells enter the central nervous system has been an unanswere […]
Research has shown for the first time that a tiny piece of RNA deregulates energy metabolism, an emerging hallmark of cancer. The finding identifies a new target for therapeutic intervention in breast cancer.
High bitter-taste sensitivity is associated with a significantly increased risk of cancer in older British women, according to researchers who conducted a unique study of 5,500 women whose diet, lifestyle and health has been tracked for about 20 years.