For years, scientists have used cells grown in petri dishes to study the metabolic processes that fuel the immune system. But a new report suggests looking outside the dish and into living organisms gives a drastically different view of the way immune cells process and use energy.
A group of physicists have used Monte Carlo modelling to produce a consistent theoretical interpretation of accurate experimental measurements of ion beams in liquid water, which is the most relevant substance for simulating interactions with human tissue.
As tumor cells multiply, they often spawn tens of thousands of genetic mutations. Figuring out which ones are the most promising to target with immunotherapy is like finding a few needles in a haystack. Now a new model hand-picks those needles so they can be leveraged in more effective, customized cancer vaccines.
Using virtual, cloud-based, interconnected computing techniques applied to 51,000 variables, researchers reduced the time needed to assess a cancer patient's tumor profile and suitability for clinical trials from 14 to 4 days. This method also increased two-fold, over a four-year period, the number of cases that could be assessed compared to conventiona […]